TEACHING

QP322 - Organic Synthesis (Graduate level)

When? Every 2nd semester of the year.

Prerequisite: BSc in Chemistry + QP021

Syllabus: Synthetic strategies in organic chemistry. Retrosynthetic analysis, discussion of synthetic routes analyzing different strategies for a common target molecule, while also understanding the classical and modern synthetic methods employed. Stereochemical control and reaction mechanisms.

QO321 - Organic Chemistry 1 (Undergraduate level)

When? Every 2nd semester of the year

Prerequisite: General Chemistry (QG-101 or 102 or 108)

Syllabus: Introduction to the discipline: some historical aspects and structural theory. Electronic structure and chemical bond. Organic structures. Alkanes and their most common reactions. Conformational analysis,  organic halides, structure and physical properties of alkyl halides, Grignard Reagents and organolithium compounds: preparation and reactivity. Nucleophilic substitutions and eliminations. Alcohols and ethers. Alkenes, alkynes and nitriles.

Suggested book: J. Clayden, N. Greeves, S. Warren, Organic Chemistry, 2nd ed., Oxford Press.  

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QO521 - Organic Chemistry 2 (Undergraduate level)

When? Every 1st semester of the year

Prerequisite: Organic Chemistry 1 (QO-321)

Syllabus: Reactivity of aldehydes, ketones, carboxylic acids and their derivatives, conjugation, allylic systems, dienes, polyenes, unsaturated carbonyl compounds, Diels-Alder reactions. Benzene, aromaticity and electrophilic aromatic substitutions. Aryl halides and the nucleophilic aromatic substitution. Phenols, amines and other nitrogenated functional groups. Structure-reactivity relationships, mechanisms of reactions,  and stereochemical considerations.

Suggested book: J. Clayden, N. Greeves, S. Warren, Organic Chemistry, 2nd ed., Oxford Press.

QO621 - Organic Chemistry 3 (Undergraduate level)

When? Every 2nd semester of the year.

Prerequisite: Organic Chemistry 2 (QO-421 or 521)

Syllabus: Molecular orbitals, revision of aromaticity. Aromatic and heteroaromatic rings, their preparation and their reactions, mainly focusing on 5 and 6-membered cycles containing one or two heteroatoms (O, N, S).

Suggested Book: J. A. Joule, K. Mills, Heterocyclic Chemistry, 5th ed., Wiley-VCH

QO622 - Laboratory of Organic Chemistry (Undergraduate level)

When? Every 2nd semester of the year.

Prerequisite: Experimental Organic and Inorganic Chemistry (QG-564 or 565) or Fundamentals of Mass Spectrometry (QO-423) or Fundamentals of NMR and other Spectroscopic Methods (QO-424).

Syllabus: Elucidation of chemical structure by 1H, 13C NMR, IR, MS. Projects in organic synthesis for the preparation of some natural compounds.

Material: QO622 Handout (in portuguese)